Prices for Zofran ODT – A 30-tablet supply of Zofran ODT oral tablet, disintegrating 4 mg costs around $696, depending on the drugstore you visit. Prices are only applicable for cash-paying consumers; insurance policies are not accepted. This Zofran ODT cost guide is based on the use of the Drugs.com discount card, which is accepted at the majority of U.S. pharmacies.
What does ondansetron cost?
Depending on the drugstore you visit, ondansetron injectable solution (2 mg/mL) costs roughly $14 for a 20-milliliter supply. Injectable Solution.
|10 (5 x 2 milliliters)||$1.46||$14.56|
|20 milliliters||$0.71 – $0.72||$14.22 – $14.49|
|48 (24 x 2 milliliters)||$1.14||$54.79|
Label for generic ondansetron. (NIH image credit) Ondansetron, sold under the trade name Zofran, is a prescription drug intended to reduce nausea and vomiting. It is frequently administered to cancer patients to avoid the nausea produced by chemotherapy, radiation treatment, and surgery.
It is occasionally recommended to pregnant women experiencing morning sickness. Zofran is a serotonin 5-HT 3 receptor antagonist that prevents nausea and vomiting by inhibiting serotonin’s action. Dr. Nagashree Seetharamu, an oncologist at the North Shore Long Island Jewish Cancer Institute in Lake Success, New York, stated, “When chemotherapy is delivered, it can release serotonin from numerous systems,” including the stomach, intestine, and brain.
When serotonin is released, it might trigger a reflex of vomiting. “Zofran can prevent this by interfering with the aforementioned mechanism,” she stated. Dosage Zofran is available as an oral tablet, an orally disintegrating tablet (ODT), a liquid, and on rare occasions as an injection.
Typically, the first dosage is administered 30 minutes before to the start of chemotherapy, one to two hours prior to the start of radiation therapy, or one hour prior to surgery. Occasionally, patients take extra dosages one to three times per day throughout chemotherapy or radiation therapy and for one to two days after treatment has concluded.
Adults normally take one 8-mg tablet, rapid-release tablet, or 10 mL of liquid twice day. Patients aged 12 and older receive the same dose as adults. Patients between the ages of 4 and 11 should take a 4-mg pill, a fast dissolving tablet, or 5 mL of liquid three times daily.
- Zofran may be used with or without meals, and patients may continue their usual diet while taking the medication.
- Patients should minimize their alcohol intake.
- Patients should take a missed dosage of Zofran as soon as possible, unless it is almost time for the following dose, in which case they should forgo the missed dose.
If a missing dosage causes nausea or vomiting, the patient should take the missed dose as quickly as possible. Zofran ODT Zofran ODT is a fast-dissolving tablet that dissolves swiftly on the tongue. It is essential that Zofran dissolve quickly on the tongue.
According to Seetharamu, some cancer patients have difficulties swallowing medications, and it is not always convenient for them to visit a medical institution to obtain injections. Those who use fast dissolving pills must be cautious when removing the tablet from its packaging. It is vital not to press the foil backing of the pill, but to peel it back with dry fingertips.
Remove the pill carefully and lay it on the top of the tongue immediately. The pill will disintegrate shortly thereafter. It may be ingested through saliva. Taking Zofran ODT with water may increase the likelihood of experiencing a headache. Side effects Zofran is connected with a number of adverse effects.
The following adverse effects are more severe. Patients should visit their physicians promptly if they experience:
- Eyesight impairment or vision loss
- Eye, face, lip, tongue, throat, hand, foot, ankle, or lower leg enlargement
- breathing or swallowing problems
- Insufficiency of breath
- loud, shrill respiration
Zofran is contraindicated for those using antidepressants or other drugs that interact with serotonin. Combining these drugs can cause serotonin syndrome, which occurs when excessive serotonin builds up in the body. According to Seetharamu and the Mayo Clinic, symptoms vary from shivering and diarrhea to stiff muscles, fever, and convulsions. Symptoms of Zofran overdose include:
- A momentary loss of eyesight that occurs suddenly
- Vertigo and lightheadedness
- erratic heart rate
Those who suspect a Zofran overdose should immediately contact emergency services or poison control. Zofran and gestation Pregnant women who suffer from morning sickness may be administered Zofran. It is available in tablet, liquid, and orally disintegrating tablet formulations (ODT).
Although Zofran is frequently successful in reducing nausea and vomiting in pregnant women, the drug’s safety for the unborn is currently under investigation. In a research conducted in January 2012, more than 4,500 pregnant women who had nausea and vomiting were compared to more than 5,800 controls.
Taking ondansetron during the first trimester of pregnancy was connected with a risk of birth abnormalities such as cleft lip or palate that was double that of women who did not take the medication. A February 2013 research, however, revealed no substantial risk of unfavorable fetal outcomes among Zofran-using moms.
In 2013, the FDA disclosed a potential safety risk for mothers taking Zofran, but was cautious to clarify that “listing a medicine with a potential safety issue does not imply FDA is saying prescribers should not prescribe the prescription or patients should stop taking the medication.” It is uncertain if Zofran passes via breast milk.
Women who have questions regarding Zofran during pregnancy should see their physicians. Additional reporting by staff writer Laura Geggel She is on Twitter as @LauraGeggel. Follow Live Science on Twitter, Facebook, and Google Plus. Additional materials
- Learn more about Zofran’s oral and intravenous administration at the Mayo Clinic.
- According to Lawyers and Settlements, more claims are being brought about purported birth abnormalities.
- National Institutes of Health: ondansetron information.
Is Zofran 4 mg available over the counter?
Zofran is a nonprescription medication. Zofran is used to relieve nausea and vomiting in adults and children older than one year who are undergoing radiation treatment for cancer.